Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092993 | 0.80 | HTR2B (0.44) | GRIN1GRIN2BATMCCR3DRD2 | |
| SCHEMBL8095854 | 0.77 | KDM4E (0.46) | GRIN1GRIN2BATMKMT2AMEN1 | |
| SCHEMBL8097090 | 0.76 | DRD4 (0.37) | KMT2AMEN1DRD4ACHEPHGDH | |
| SCHEMBL8102177 | 0.76 | GPR6 (0.47) | ATMKMT2AMEN1KDM4ESLC6A4 | |
| SCHEMBL8101941 | 0.75 | KDM4E (0.45) | ATMKMT2AMEN1HTR2CHTR7 | |
| SCHEMBL8095852 | 0.72 | CCR3 (0.47) | GRIN1GRIN2BATMKMT2AMEN1 | |
| SCHEMBL8091662 | 0.71 | HRH1 (0.47) | KMT2ADRD4CCR3HRH1 | |
| SCHEMBL8095680 | 0.69 | PDE4B (0.46) | ATMKMT2AMEN1ACHEHTR2C | |
| SCHEMBL13945410 | 0.67 | MEN1 (0.39) | ATMKMT2AMEN1DRD4CCR3 | |
| SCHEMBL13968360 | 0.66 | OPRL1 (0.42) | KMT2AMEN1DRD4CCR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |