Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 4/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945358 | 0.85 | AR (0.40) | KDM4EKMT2AMAPTMEN1HTR2B | |
| SCHEMBL8101941 | 0.79 | KDM4E (0.45) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8092993 | 0.78 | HTR2B (0.44) | HTR2BHTR3AHTR4HTR2CGRIN1 | |
| SCHEMBL8102227 | 0.77 | GRIN1 (0.42) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8102177 | 0.76 | GPR6 (0.47) | KDM4EKMT2AMEN1HTR1AATM | |
| SCHEMBL8095852 | 0.74 | CCR3 (0.47) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8091662 | 0.71 | HRH1 (0.47) | KMT2AALDH1A1CCR3HRH1 | |
| SCHEMBL8093682 | 0.71 | SCN5A (0.40) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8102279 | 0.70 | HTR2B (0.42) | KMT2AMEN1HTR2BHTR3AHTR4 | |
| SCHEMBL8096499 | 0.68 | GAA (0.53) | KMT2ASMN1; SMN2MEN1HTR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |