Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871015 | 0.88 | TSHR (0.40) | TSHRALDH1A1MAPTTDP1 | |
| SCHEMBL7027251 | 0.88 | MEN1 (0.45) | ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL4163594 | 0.86 | HPGDS (0.42) | ALDH1A1MAPTTDP1 | |
| SCHEMBL7030199 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTTDP1 | |
| SCHEMBL14268976 | 0.83 | HTR1A (0.44) | TSHRALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL14268974 | 0.83 | TDP1 (0.41) | TSHRALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL4867949 | 0.82 | CYP2E1 (0.43) | TSHRALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL4862725 | 0.82 | HTR1A (0.43) | TSHRALDH1A1KMT2ATDP1 | |
| SCHEMBL4870569 | 0.82 | HPGD (0.39) | TSHRALDH1A1KMT2ATDP1 | |
| SCHEMBL13851862 | 0.81 | TDP1 (0.42) | TSHRALDH1A1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |