Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.64 |
| ▸ | RXRB | P28702 | 14/20 | 0.64 |
| ▸ | RXRG | P48443 | 10/20 | 0.64 |
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | RARG | P13631 | 6/20 | 0.56 |
| ▸ | RARA | P10276 | 4/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102921 | 0.90 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5080288 | 0.89 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8102435 | 0.88 | RXRA (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5084705 | 0.88 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8102485 | 0.88 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8103047 | 0.87 | RXRA (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8100910 | 0.84 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8102605 | 0.84 | RXRA (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839060 | 0.84 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8102771 | 0.84 | ALDH1A1 (0.51) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661260-B1 | New bi-aromatic compounds derived from amides pharmaceutical compositions and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1997-03-12 | — | — | EP | claimed |
| JP-8027085-A | — | — | None | — | — | JP | disclosed |
| US-6051243-A | USEFUL IN THE TOPICAL AND SYSTEMIC TREATMENT OF DERMATOLOGICAL CONDITIONS ASSOCIATED WITH A KERATINIZATION DISORDER, DERMATOLOGICAL CONDITIONS (AND THE LIKE) INCLUDING AN INFLAMMATORY AND/OR IMMUNOALLERGIC COMPONENT | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-04-18 | — | — | US | disclosed |
| JP-H0827085-A | NEW DIAROMATIC COMPOUNDS DERIVED FROM AMIDE, PHARMACEUTICAL/COSMETIC COMPOSITION CONTAINING THE SAME AND THEIR USE | CIRD GALDERMA | 1996-01-30 | — | — | JP | disclosed |