Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.49 |
| ▸ | EIF4A1 | P60842 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277951 | 0.81 | APP (0.44) | ALDH1A1TSHR | |
| SCHEMBL6321027 | 0.80 | ACHE (0.50) | NPBWR1ALDH1A1TSHR | |
| SCHEMBL8072424 | 0.78 | POLB (0.39) | NPBWR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL6493292 | 0.78 | CNR1 (0.40) | ALDH1A1ALOX5 | |
| SCHEMBL11385468 | 0.77 | POLB (0.46) | NPBWR1ALDH1A1TSHRALOX5 | |
| SCHEMBL5461460 | 0.77 | GABRP (0.46) | ALDH1A1TSHRKDM4EALOX5 | |
| SCHEMBL14880550 | 0.77 | ALDH1A1 (0.44) | NPBWR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL10577172 | 0.77 | HSPB1 (0.42) | ALDH1A1TSHRKDM4E | |
| SCHEMBL5096848 | 0.77 | ALDH1A1 (0.47) | NPBWR1ALDH1A1TSHR | |
| SCHEMBL9476182 | 0.77 | APP (0.50) | NPBWR1ALDH1A1KDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |