Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
| ▸ | LIPC | P11150 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 3/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088605 | 0.85 | AR (0.32) | GPR119GPR6SLC6A9KCNH2 | |
| SCHEMBL8081429 | 0.80 | GPR119 (0.51) | GPR119ALDH1A1LIPESCN9A | |
| SCHEMBL7333661 | 0.79 | OXTR (0.42) | GPR119RXRAALDH1A1POLBLIPE | |
| SCHEMBL8094956 | 0.78 | LIPG (0.38) | GPR119LIPGLIPCKCNH2LPL | |
| SCHEMBL7333820 | 0.76 | OXTR (0.41) | ALDH1A1POLBLIPECNR2ACACB | |
| SCHEMBL3563776 | 0.76 | GRIK1 (0.43) | ALDH1A1GPR6HTR2A | |
| SCHEMBL3901739 | 0.75 | GPR6 (0.36) | LIPGLIPCALDH1A1GPR6 | |
| SCHEMBL3557510 | 0.73 | GPR6 (0.35) | GPR119GPR6 | |
| SCHEMBL8089498 | 0.72 | GPR119 (0.51) | GPR119LIPESCN9APREP | |
| SCHEMBL8088578 | 0.70 | EPHX2 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |