Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.38 |
| ▸ | LIPC | P11150 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081388 | 0.87 | EPHX2 (0.40) | HRH3GPR119EPHX2HRH1CCR3 | |
| SCHEMBL8088578 | 0.86 | EPHX2 (0.40) | HRH3GPR119EPHX2 | |
| SCHEMBL8089444 | 0.84 | AR (0.46) | — | |
| SCHEMBL8092927 | 0.83 | EPHX2 (0.37) | HRH3EPHX2NEK2 | |
| SCHEMBL3563776 | 0.82 | GRIK1 (0.43) | — | |
| SCHEMBL8088615 | 0.82 | EPHX2 (0.36) | HRH3GPR119EPHX2 | |
| SCHEMBL3901739 | 0.79 | GPR6 (0.36) | LIPGLIPC | |
| SCHEMBL7333661 | 0.78 | OXTR (0.42) | GPR119HRH1CCR3KCNH2 | |
| SCHEMBL7356525 | 0.78 | HIF1A (0.34) | HRH3GPR119 | |
| SCHEMBL8093281 | 0.78 | GPR119 (0.32) | LIPGLIPCGPR119LPLKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |