⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103217 | 0.97 | — | — | |
| SCHEMBL8101322 | 0.91 | — | — | |
| SCHEMBL8109276 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL8103219 | 0.73 | ADORA3 (0.39) | — | |
| SCHEMBL7468232 | 0.70 | ADRA2A (0.33) | — | |
| SCHEMBL8107605 | 0.68 | HRH3 (0.37) | — | |
| SCHEMBL8101449 | 0.68 | MYC (0.40) | — | |
| SCHEMBL8103450 | 0.68 | CHRM2 (0.42) | — | |
| SCHEMBL7468021 | 0.68 | CHRM2 (0.39) | — | |
| SCHEMBL7473528 | 0.67 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |