Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101364 | 0.77 | KDM4E (0.40) | KDM4E | |
| SCHEMBL7468021 | 0.76 | CHRM2 (0.39) | CHRM2TSHRSCN8A | |
| SCHEMBL8103450 | 0.74 | CHRM2 (0.42) | CHRM2TSHRSCN8A | |
| SCHEMBL7467923 | 0.73 | CHRM2 (0.44) | CHRM2TSHRSCN8A | |
| SCHEMBL8101368 | 0.72 | TRIM24 (0.39) | KDM4E | |
| SCHEMBL8103219 | 0.71 | ADORA3 (0.39) | — | |
| SCHEMBL7473528 | 0.70 | CHRM2 (0.35) | CHRM2TSHRSCN8A | |
| SCHEMBL8093553 | 0.70 | ADORA3 (0.31) | — | |
| SCHEMBL8101449 | 0.69 | MYC (0.40) | — | |
| SCHEMBL8093555 | 0.69 | GRM5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |