Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103219 | 0.78 | ADORA3 (0.39) | ADORA3ADORA2AADORA1BRD4KMT2A | |
| SCHEMBL8101449 | 0.76 | MYC (0.40) | ADORA3ADORA2AADORA1KMT2A | |
| SCHEMBL8101368 | 0.76 | TRIM24 (0.39) | ADORA3ADORA2AADORA1BRD4KMT2A | |
| SCHEMBL8093555 | 0.76 | GRM5 (0.33) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8101364 | 0.73 | KDM4E (0.40) | BRD4 | |
| SCHEMBL8109284 | 0.72 | GAA (0.37) | ADORA3ADORA2AADORA1KMT2A | |
| SCHEMBL8093773 | 0.70 | CHRM2 (0.33) | — | |
| SCHEMBL8103161 | 0.70 | KDM4E (0.40) | KMT2A | |
| SCHEMBL8109287 | 0.70 | KMT2A (0.40) | KMT2A | |
| SCHEMBL8101458 | 0.70 | GRM5 (0.33) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |