SCHEMBL8094028

SCHEMBL8094028

CC(CC(C)(C)C)CP(=S)(CC(C)CC(C)(C)C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14182835 0.72
SCHEMBL8774149 0.68 LMNA (0.36) LMNAALDH1A1PKMKMT2AHTT
SCHEMBL4065609 0.68
SCHEMBL2452422 0.67 SIGMAR1 (0.50) MEN1KMT2A
SCHEMBL25365713 0.66
SCHEMBL665109 0.66
SCHEMBL662002 0.66
SCHEMBL2561994 0.65 ALDH1A1 (0.56) LMNATSHRALDH1A1MEN1GAA
SCHEMBL10946747 0.65
Ammonia Solution, Strong SCHEMBL10941592 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732336-B1 Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides CYTEC CANADA INC (CA) 2000-12-20 EP disclosed
EP-0732336-A1 Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides Cytec Canada Inc. (CA) 1996-09-18 EP disclosed
US-5550295-A Preparation of arylalkyl phosphines, phosphine oxides or phosphine sulfides CYTEC TECHNOLOGY CORP. (US) 1996-08-27 US disclosed