Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774242 | 0.73 | — | — | |
| SCHEMBL8178989 | 0.71 | PSIP1 (0.40) | SMN1; SMN2PSIP1ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL8774090 | 0.70 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2MITFKMT2APSIP1 | |
| SCHEMBL11483763 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1KDM4EMAPTCYP2C19 | |
| SCHEMBL8094028 | 0.68 | RIPK1 (0.34) | LMNASMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL27561635 | 0.67 | HSD11B1 (0.39) | LMNAKMT2AALDH1A1HSD11B1MMP2 | |
| SCHEMBL2990037 | 0.66 | — | — | |
| SCHEMBL28339252 | 0.66 | MMP1 (0.38) | LMNAKMT2AALDH1A1HSD11B1MMP2 | |
| SCHEMBL28807013 | 0.66 | HSD11B1 (0.43) | SMN1; SMN2PSIP1ALDH1A1HSD11B1CYP2C19 | |
| SCHEMBL2446368 | 0.65 | PSIP1 (0.60) | KMT2AHPGDPSIP1ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805159-A1 | Phosphorus containing alkyl or arylsulphonyl derivatives and method for preparing same | Cytec Canada Inc. (CA) | 1997-11-05 | — | — | EP | disclosed |