Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31253313 | 0.86 | PGR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11268130 | 0.84 | PGR (0.49) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL268856 | 0.83 | MDM2 (0.57) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL1801672 | 0.82 | LMNA (0.56) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL8935027 | 0.82 | TRPA1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10345706 | 0.82 | LMNA (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL6899911 | 0.82 | MDM2 (0.55) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10825050 | 0.81 | PGR (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL13130583 | 0.81 | PGR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2736655 | 0.81 | L3MBTL1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3665163-A1 | USE OF AMBROCENIDE ® FOR INTENSIFYING A LILY OF THE VALLEY SCENT | Symrise AG (DE) | 2020-06-17 | — | — | EP | claimed |
| EP-0254432-A2 | Method of preparing alpha-arylalkanoic esters | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | claimed |
| JP-57163337-A | — | — | None | — | — | JP | disclosed |
| CN-107074712-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-107074713-B | Phenyl-based compounds substituted with aldehyde moieties and their use in perfumery | 奇华顿股份有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-107074714-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111788305-A | Lipase variants and compositions thereof | 诺维信公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111670248-A | Lipase variants and polynucleotides encoding same | 诺维信公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-111601887-A | Alpha-amylase variants and polynucleotides encoding same | 诺维信公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-107074732-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-111500552-A | Polypeptides having lipase activity and polynucleotides encoding same | 诺维信公司 | 2020-08-07 | — | — | CN | disclosed |
| EP-3665163-A1 | USE OF AMBROCENIDE ® FOR INTENSIFYING A LILY OF THE VALLEY SCENT | Symrise AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |
| EP-0254432-A2 | Method of preparing alpha-arylalkanoic esters | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0048136-B1 | PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-06-11 | — | — | EP | disclosed |
| JP-S57163337-A | PREPARATION OF PROPIONIC ACID DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1982-10-07 | — | — | JP | disclosed |