Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580361 | 0.88 | L3MBTL1 (0.59) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL19659491 | 0.86 | LMNA (0.50) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL633843 | 0.85 | MEN1 (0.51) | LMNAALDH1A1SMN1; SMN2ATMHRH1 | |
| SCHEMBL633842 | 0.85 | MEN1 (0.58) | LMNAHSD17B10ALDH1A1ATMHRH1 | |
| SCHEMBL8094352 | 0.82 | PGR (0.52) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1716112 | 0.82 | CYP2C19 (0.53) | LMNAALDH1A1SMN1; SMN2CTSSCTSK | |
| SCHEMBL29832525 | 0.81 | L3MBTL1 (0.52) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2120942 | 0.81 | CTSS (0.49) | LMNAHSD17B10ALDH1A1CTSSCTSK | |
| SCHEMBL10345706 | 0.81 | LMNA (0.53) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL50454 | 0.81 | LMNA (0.80) | LMNAHSD17B10TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760899-B1 | COATING COMPOSITION AND USE THEREOF | PPG EUROPE B V (NL) | 2020-08-19 | — | — | EP | disclosed |
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | ADC BIOTECHNOLOGY LTD. (GB) | 2017-07-13 | — | — | US | disclosed |
| EP-1778751-B1 | CARBOHYDRATE BASED ALKYDS | SHERWIN-WILLIAMS LUXEMBOURG INVEST MAN COMPANY S À R L (LU) | 2017-03-01 | — | — | EP | disclosed |
| US-9145501-B2 | Coating composition and use thereof | PPG EUROPE BV (NL) | 2015-09-29 | — | — | US | disclosed |
| US-20140221520-A1 | Coating Composition and Use Thereof | PPG EUROPE BV (NL) | 2014-08-07 | — | — | US | disclosed |
| EP-2760899-A1 | COATING COMPOSITION AND USE THEREOF | PPG Europe B.V. (NL) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013045475-A1 | COATING COMPOSITION AND USE THEREOF | PPG EUROPE BV (NL) | 2013-04-04 | — | — | WO | disclosed |
| US-7951429-B2 | High energy curable coatings comprising thermoplastic polymers | THE SHERWIN-WILLIAMS COMPANY (US) | 2011-05-31 | — | — | US | disclosed |
| US-20090214877-A1 | HIGH ENERGY CURABLE COATINGS COMPRISING THERMOPLASTIC POLYMERS | THE SHERWIN-WILLIAMS COMPANY (US) | 2009-08-27 | — | — | US | disclosed |
| US-7527864-B2 | High energy curable coatings comprising thermoplastic polymers | THE SHERWIN-WILLIAMS COMPANY (US) | 2009-05-05 | — | — | US | disclosed |
| US-20060036029-A1 | Carbohydrate based alkyds | SHERWIN-WILLIAMS COMPANY, THE | 2006-02-16 | — | — | US | disclosed |
| US-20050209358-A1 | High energy curable coatings comprising thermoplastic polymers | SHERWIN-WILLIAMS COMPANY THE | 2005-09-22 | — | — | US | disclosed |
| WO-2005087875-A1 | HIGH ENERGY CURABLE COATINGS COMPRISING THERMOPLASTIC POLYMERS | THE SHERWIN-WILLIAMS COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-6787225-B2 | MIXTURE CONTAINING PHOTOINTIATOR AND WAX | THE SHERWIN-WILLIAMS COMPANY | 2004-09-07 | — | — | US | disclosed |
| US-20030054116-A1 | Radiation curable coating having low gloss and coated articles made therefrom | THE SHERWIN-WILLIAMS COMPANY | 2003-03-20 | — | — | US | disclosed |
| US-6448302-B1 | DI- AND/OR TRIACRYLATED MONOMERS, INITIATOR, WAX AND UNSATURATED SILANE SURFACE TREATED PIGMENT; EXPOSURE TO RADIATION IN PRESENCE OF OXYGEN; LOW GLOSS, SMOOTH, ABRASION RESISTANT SHEET WHICH CAN ERASIBLY MARKED | THE SHERWIN-WILLIAMS COMPANY | 2002-09-10 | — | — | US | disclosed |
| WO-2001053421-A1 | RADIATION CURABLE COATINGS HAVING LOW GLOSS AND COATED ARTICLES MADE THEREFROM | THE SHERWIN-WILLIAMS COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |
| US-5559163-A | PHOTOINITIATOR, UNSATURATED PHOTOPOLYMERIZABLE UV ABSORBER, ACRYLIC MONOMER, SILICA | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| US-4601797-A | Electrochemical carboxylation of p-isobutylacetophenone and other aryl ketones | MONSANTO COMPANY (US) | 1986-07-22 | — | — | US | disclosed |
| US-4582577-A | Electrochemical carboxylation of p-isobutylacetophenone | MONSANTO COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196990-A1 | METHOD OF SYNTHESISING ADCS USING PHOTOCLEAVABLE LINKERS ON SOLID SUPPORT | SBDS, ADCY8, DCK | LMNA 2775/4885HSD17B10 3595/4885TDP1 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.