SCHEMBL8094360

SCHEMBL8094360

CCCc1ccc(Cl)c(Cl)c1C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.33
TAAR1 Q96RJ0 1/20 0.32
PRKCI P41743 1/20 0.32
CTRC Q99895 1/20 0.32
TYR P14679 1/20 0.32
PNMT P11086 2/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ALOX15 P16050 1/20 0.30
METAP2 P50579 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089662 0.88 CTRC (0.44) ALOX5CTRCTYRALOX15METAP2
SCHEMBL8082902 0.82 CTRC (0.39) CTRCPNMTSLC6A2SLC6A4CYP3A4
SCHEMBL10061111 0.82 TAAR1 (0.39) TAAR1PRKCICTRCPNMTSLC6A2
SCHEMBL20563034 0.81 TAAR1 (0.53) TAAR1PNMTMAPK1
SCHEMBL22336230 0.79 METAP2 (0.34) ALOX5PRKCICTRCTYRMETAP2
SCHEMBL4337373 0.76 PDCD1 (0.39) PNMTSLC6A2SLC6A4CYP3A4MAPK1
SCHEMBL900037 0.75 ALDH1A1 (0.42) PNMTSLC6A4CYP3A4MAPK1
SCHEMBL8107061 0.75 ATP4A (0.39) ALOX5PRKCICTRCTYRCYP3A4
SCHEMBL8082953 0.74 CYP3A4 (0.36) ALOX5ALOX15CYP3A4MAPK1
SCHEMBL8094251 0.74 ALDH1A1 (0.45) TAAR1PNMTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed