Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701616 | 0.88 | AGTR2 (0.54) | AGTR2AGTR1 | |
| SCHEMBL8088528 | 0.88 | — | — | |
| SCHEMBL8083218 | 0.87 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL8088442 | 0.85 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL8089404 | 0.85 | AGTR2 (0.74) | AGTR2AGTR1 | |
| SCHEMBL482 | 0.81 | AGTR1 (0.46) | AGTR2AGTR1 | |
| SCHEMBL215 | 0.80 | AGTR1 (0.63) | AGTR2AGTR1 | |
| SCHEMBL605 | 0.80 | AGTR1 (0.58) | AGTR2AGTR1 | |
| SCHEMBL358 | 0.79 | AGTR1 (0.72) | AGTR2AGTR1 | |
| SCHEMBL8081250 | 0.79 | AGTR2 (0.72) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| EP-0505893-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1992-09-30 | — | — | EP | disclosed |