Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088442 | 0.89 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL8094878 | 0.88 | AGTR2 (0.58) | AGTR2AGTR1 | |
| SCHEMBL8709031 | 0.87 | AGTR1 (0.42) | AGTR2AGTR1 | |
| SCHEMBL8708854 | 0.85 | AGTR1 (0.50) | AGTR2AGTR1 | |
| SCHEMBL8088528 | 0.76 | — | — | |
| SCHEMBL8092915 | 0.76 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL8083218 | 0.76 | AGTR1 (0.49) | AGTR2AGTR1 | |
| SCHEMBL8094791 | 0.75 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL8094963 | 0.75 | AGTR2 (0.68) | AGTR2AGTR1 | |
| SCHEMBL8092760 | 0.75 | AGTR2 (0.65) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798364-A | ANGIOTENSIN II ANTAGONIST, USEFUL FOR TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-08-25 | — | — | US | disclosed |