Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094862 | 0.85 | ALDH1A1 (0.36) | DPP4ALDH1A1MAPT | |
| SCHEMBL8095366 | 0.83 | MCL1 (0.40) | HSD11B1ALDH1A1MAPT | |
| SCHEMBL8438547 | 0.81 | HSD11B1 (0.41) | HSD11B1TDP1EPHX2DPP8DPP9 | |
| SCHEMBL8438145 | 0.81 | HSD11B1 (0.41) | HSD11B1TDP1EPHX2DPP8DPP9 | |
| SCHEMBL8438142 | 0.81 | HSD11B1 (0.41) | HSD11B1TDP1EPHX2DPP8DPP9 | |
| SCHEMBL8104455 | 0.80 | HSD11B1 (0.37) | HSD11B1TDP1EPHX2DPP8DPP9 | |
| SCHEMBL7455087 | 0.79 | CTRB1 (0.42) | CTSKCTSBCTSSALDH1A1MAPT | |
| SCHEMBL8102832 | 0.79 | CTRB1 (0.42) | CTSKCTSBCTSSALDH1A1MAPT | |
| SCHEMBL7455094 | 0.79 | CTRB1 (0.42) | CTSKCTSBCTSSALDH1A1MAPT | |
| SCHEMBL8102837 | 0.79 | CTRB1 (0.42) | CTSKCTSBCTSSALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |