Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | FPR2 | P25090 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094980 | 0.85 | TP53 (0.52) | RAB9AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8089925 | 0.85 | ALDH1A1 (0.50) | RAB9AFPR2MEN1KMT2ALMNA | |
| SCHEMBL21104548 | 0.85 | ACP1 (0.56) | RAB9AMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8083324 | 0.84 | FPR2 (0.56) | RAB9AFPR2MEN1KMT2ALMNA | |
| SCHEMBL8095025 | 0.83 | FPR2 (0.55) | RAB9AFPR2MEN1KMT2ALMNA | |
| SCHEMBL8095034 | 0.79 | EPHX1 (0.55) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL9339228 | 0.76 | FAAH (0.41) | RAB9AFPR2MEN1KMT2APOLB | |
| SCHEMBL9341223 | 0.73 | NPC1 (0.48) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL22175221 | 0.72 | FPR2 (1.00) | RAB9AFPR2MEN1KMT2ALMNA | |
| SCHEMBL16020523 | 0.72 | FPR2 (1.00) | RAB9AFPR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147115-A | SULFONYLUREIDO-4-HALOBENZENE DERIVATIVES; ANTICARCINOGENIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0467621-B1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | LILLY CO ELI (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5216026-A | Administering to the mammal N-1-butanesulfonamide derivatives and salts | ELI LILLY AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0467621-A1 | N-phenyl-N'-alkylsulfonylureas, process for their preparation and antitumor compositions containing them | ELI LILLY AND COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |