Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519289 | 0.88 | CTSB (0.62) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL8095201 | 0.87 | MAPT (0.50) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL8103840 | 0.86 | ALDH1A1 (0.70) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL16943039 | 0.81 | CTSB (0.57) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL3984049 | 0.78 | CYP1A2 (0.54) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL3154116 | 0.78 | MAPT (0.64) | CTSBMAPTALDH1A1HTTCYP2C9 | |
| SCHEMBL3718871 | 0.78 | MAPT (0.63) | CTSBMAPTALDH1A1HTTKDM4E | |
| SCHEMBL1424205 | 0.75 | ALDH1A1 (0.50) | CTSBMAPTALDH1A1POLBHTT | |
| SCHEMBL30206335 | 0.75 | MAPT (0.57) | CTSBMAPTALDH1A1HTTKDM4E | |
| SCHEMBL6511388 | 0.75 | MAPT (0.57) | CTSBMAPTALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |