Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.55 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17342646 | 0.97 | USP2 (0.56) | ERCC1ERCC4CCR2USP2ALDH1A1 | |
| SCHEMBL5275905 | 0.94 | CCR2 (0.59) | ERCC1ERCC4CCR2USP2ALDH1A1 | |
| SCHEMBL15844342 | 0.88 | ALDH1A1 (0.54) | CCR2ALDH1A1MTORLMNAPOLB | |
| Formic Acid SCHEMBL5676537 | 0.88 | CCR2 (0.55) | CCR2USP2ALDH1A1HPGDKDM4E | |
| SCHEMBL15844868 | 0.85 | HTR2C (0.51) | CCR2MTORLMNAPOLBGAA | |
| SCHEMBL5526975 | 0.85 | KDM4E (0.65) | ERCC1ERCC4USP2ALDH1A1HPGD | |
| SCHEMBL5534711 | 0.84 | HDAC6 (0.66) | ERCC1ERCC4USP2ALDH1A1HPGD | |
| SCHEMBL13818163 | 0.84 | LMNA (0.51) | CCR2HPGDMTORLMNAPOLB | |
| SCHEMBL17048662 | 0.83 | KDM4E (0.53) | ERCC1ERCC4CCR2USP2ALDH1A1 | |
| SCHEMBL17048513 | 0.82 | WDR5 (0.53) | ERCC1ERCC4CCR2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |