Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.37 |
| ▸ | FNTB | P49356 | 6/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095949 | 1.00 | FNTA (0.37) | FNTAFNTBCHRM4CHRM2CHRM5 | |
| SCHEMBL8097906 | 0.93 | L3MBTL1 (0.39) | FNTAFNTBCHRM4PGGT1B | |
| SCHEMBL8097913 | 0.93 | L3MBTL1 (0.39) | FNTAFNTBCHRM4PGGT1B | |
| SCHEMBL8104363 | 0.91 | CYP19A1 (0.39) | FNTAFNTBCHRM4 | |
| SCHEMBL8104371 | 0.91 | CYP19A1 (0.39) | FNTAFNTBCHRM4 | |
| SCHEMBL8097065 | 0.90 | CYP19A1 (0.36) | FNTAFNTB | |
| SCHEMBL8097062 | 0.90 | CYP19A1 (0.36) | FNTAFNTB | |
| SCHEMBL8103769 | 0.90 | CYP19A1 (0.36) | FNTAFNTB | |
| SCHEMBL8102234 | 0.89 | RAB9A (0.36) | FNTAFNTBPGGT1BJAK2 | |
| SCHEMBL8102230 | 0.89 | RAB9A (0.36) | FNTAFNTBPGGT1BJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |