Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 10/20 | 0.33 |
| ▸ | FNTB | P49356 | 10/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.33 |
| ▸ | CLPP | Q16740 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102234 | 1.00 | RAB9A (0.36) | RAB9APDCD1CD274FNTAFNTB | |
| SCHEMBL8095942 | 0.89 | FNTA (0.37) | FNTAFNTBPGGT1BJAK2 | |
| SCHEMBL8095949 | 0.89 | FNTA (0.37) | FNTAFNTBPGGT1BJAK2 | |
| SCHEMBL8097913 | 0.85 | L3MBTL1 (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8097906 | 0.85 | L3MBTL1 (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8098386 | 0.85 | CYP11B1 (0.34) | FNTAFNTB | |
| SCHEMBL8098378 | 0.85 | CYP11B1 (0.34) | FNTAFNTB | |
| SCHEMBL8097065 | 0.84 | CYP19A1 (0.36) | FNTAFNTB | |
| SCHEMBL8097062 | 0.84 | CYP19A1 (0.36) | FNTAFNTB | |
| SCHEMBL8103769 | 0.84 | CYP19A1 (0.36) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |