Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729320 | 0.82 | LMNA (0.41) | ALDH1A1MEN1KMT2ACYP2C9TSHR | |
| SCHEMBL316039 | 0.80 | GSK3A (0.41) | ALDH1A1GSK3AGSK3BCCR6MEN1 | |
| SCHEMBL20561062 | 0.75 | GSK3A (0.44) | ALDH1A1GSK3AGSK3BCCR6TSHR | |
| SCHEMBL4819951 | 0.75 | PLG (0.43) | ALDH1A1GSK3AGSK3BCCR6MEN1 | |
| SCHEMBL20002959 | 0.69 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL216544 | 0.68 | GSK3A (0.61) | ALDH1A1GSK3AGSK3BCCR6 | |
| SCHEMBL16892234 | 0.67 | TSHR (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL16892243 | 0.67 | TSHR (0.34) | TSHRSMN1; SMN2 | |
| Acetic Acid SCHEMBL29870582 | 0.65 | GSK3A (0.65) | GSK3AGSK3BCCR6 | |
| Acetic Acid SCHEMBL208214 | 0.65 | GSK3A (0.65) | GSK3AGSK3BCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071974-A2 | MONITORING IMMUNOTHERAPY OF LEWY BODY DISEASE FROM CONSTIPATION SYMPTOMS | Prothena Biosciences Limited (IE) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015075635-A2 | MONITORING IMMUNOTHERAPY OF LEWY BODY DISEASE FROM CONSTIPATION SYMPTOMS | PROTHENA BIOSCIENCES LIMITED (IE) | 2015-05-28 | — | — | WO | disclosed |
| EP-1057025-A1 | PROTEIN KINASE C | Imperial Cancer Research Technology ( ICRT) (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042833-A1 | PROTEIN KINASE C | IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1999-08-26 | — | — | WO | disclosed |