Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 12/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096223 | 1.00 | MTNR1B (0.51) | MTNR1BMTNR1ASLC9A1 | |
| SCHEMBL8096228 | 1.00 | MTNR1B (0.51) | MTNR1BMTNR1ASLC9A1 | |
| SCHEMBL8103536 | 0.87 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL8103541 | 0.87 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL18912573 | 0.84 | FFAR1 (0.45) | MTNR1BMTNR1A | |
| SCHEMBL8089150 | 0.78 | HTR2A (0.55) | MTNR1BMTNR1A | |
| SCHEMBL8088925 | 0.78 | HTR2A (0.55) | MTNR1BMTNR1A | |
| SCHEMBL6321790 | 0.76 | SLC9A1 (0.51) | SLC9A1 | |
| SCHEMBL8098006 | 0.76 | SLC9A1 (0.51) | SLC9A1 | |
| SCHEMBL8098003 | 0.76 | SLC9A1 (0.51) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |