Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103536 | 1.00 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL8096223 | 0.87 | MTNR1B (0.51) | MTNR1BMTNR1A | |
| SCHEMBL8096228 | 0.87 | MTNR1B (0.51) | MTNR1BMTNR1A | |
| SCHEMBL8096225 | 0.87 | MTNR1B (0.51) | MTNR1BMTNR1A | |
| SCHEMBL8098209 | 0.83 | MTNR1A (0.43) | MTNR1BMTNR1A | |
| SCHEMBL8098211 | 0.83 | MTNR1A (0.43) | MTNR1BMTNR1A | |
| SCHEMBL8088925 | 0.77 | HTR2A (0.55) | MTNR1BMTNR1A | |
| SCHEMBL8089150 | 0.77 | HTR2A (0.55) | MTNR1BMTNR1A | |
| SCHEMBL8334114 | 0.76 | SLC9A1 (0.41) | MTNR1BMTNR1A | |
| SCHEMBL8330356 | 0.75 | SLC9A1 (0.44) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |