Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085908 | 0.90 | BID (0.49) | BIDMCL1KAT8PPARABCL2L1 | |
| SCHEMBL8096193 | 0.88 | BID (0.55) | BIDMCL1KAT8PPARABCL2L1 | |
| SCHEMBL8093727 | 0.87 | GABRA1 (0.45) | ITGB1ITGA4GPR52F2RGABRA1 | |
| SCHEMBL8100395 | 0.87 | BID (0.57) | BIDMCL1KAT8PPARABCL2L1 | |
| SCHEMBL8096206 | 0.87 | BID (0.57) | BIDMCL1KAT8PPARABCL2L1 | |
| SCHEMBL8096083 | 0.87 | BID (0.57) | BIDMCL1KAT8PPARABCL2L1 | |
| SCHEMBL5164770 | 0.84 | BID (0.53) | ITGB1ITGA4BIDMCL1KAT8 | |
| SCHEMBL7420497 | 0.82 | ITGB1 (0.43) | ITGB1ITGA4BIDMCL1KAT8 | |
| SCHEMBL2325202 | 0.81 | GPR52 (0.38) | GPR52F2RCTBP2GABRA1GABRB2 | |
| SCHEMBL6113407 | 0.78 | L3MBTL1 (0.44) | GPR52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |