Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096357 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL8105870 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD11B1KMT2AKDM4EMAPT | |
| SCHEMBL8109654 | 0.78 | SLC6A4 (0.68) | SLC6A4HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL4677474 | 0.78 | HTR3E (0.51) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL4677480 | 0.73 | HTR3E (0.68) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL29206505 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL29206501 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL29206544 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 | |
| SCHEMBL4673257 | 0.71 | HSD11B1 (0.54) | SLC6A4HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL29206540 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2SLC6A4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |