Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103946 | 0.81 | LMNA (0.58) | FPR2PROKR1LMNAMAPT | |
| SCHEMBL4675433 | 0.81 | MMP1 (0.54) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4675437 | 0.81 | MMP1 (0.54) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL8550694 | 0.78 | MEN1 (0.48) | LMNAMAPT | |
| SCHEMBL4673322 | 0.77 | MMP1 (0.59) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4673327 | 0.77 | MMP1 (0.59) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4673329 | 0.77 | MMP1 (0.59) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4673324 | 0.77 | MMP1 (0.59) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4671106 | 0.76 | MMP1 (0.58) | MMP12MMP13MMP1FPR2PROKR1 | |
| SCHEMBL4671102 | 0.76 | MMP1 (0.58) | MMP12MMP13MMP1FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |