Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103946 | 0.79 | LMNA (0.58) | MEN1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL4671098 | 0.79 | SMN1; SMN2 (0.46) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4671091 | 0.79 | SMN1; SMN2 (0.46) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL8096415 | 0.78 | MMP12 (0.45) | MAPTLMNA | |
| SCHEMBL4673540 | 0.78 | MMP2 (0.55) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4673538 | 0.78 | MMP2 (0.55) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL28895576 | 0.78 | MEN1 (0.56) | MEN1KMT2AMMP14ADAMTS5AKR1C3 | |
| SCHEMBL8104001 | 0.77 | HRH3 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4677143 | 0.77 | SMN1; SMN2 (0.45) | MEN1KMT2AMMP14ADAMTS5MAPT | |
| SCHEMBL4677141 | 0.77 | SMN1; SMN2 (0.45) | MEN1KMT2AMMP14ADAMTS5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |