Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096541 | 0.77 | FAAH (0.51) | FAAHKMT2ACA12CA1CA2 | |
| SCHEMBL4672695 | 0.76 | KMT2A (0.50) | FAAHKMT2ACA12CA1CA2 | |
| SCHEMBL7319451 | 0.76 | KMT2A (0.50) | FAAHKMT2ACA12CA1CA2 | |
| SCHEMBL1026389 | 0.74 | MAPT (0.62) | FAAHKMT2APDGFRBMAPTSMN1; SMN2 | |
| SCHEMBL311835 | 0.73 | SMN1; SMN2 (0.66) | FAAHKMT2APDGFRBMAPTSMN1; SMN2 | |
| SCHEMBL9467061 | 0.73 | MAPT (0.74) | FAAHKMT2APDGFRBMAPTSMN1; SMN2 | |
| SCHEMBL12882928 | 0.72 | EPHX2 (0.53) | FAAHKMT2ACA12CA1CA2 | |
| SCHEMBL5912869 | 0.71 | NPY5R (0.56) | FAAHKMT2ANPY5RPDGFRBMAPT | |
| SCHEMBL28363630 | 0.70 | EPHX2 (0.67) | FAAHKMT2AGAAPDGFRBMAPT | |
| SCHEMBL20236423 | 0.70 | FAAH (0.61) | FAAHPDGFRBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |