Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672695 | 1.00 | KMT2A (0.50) | KMT2AFAAHGAANPY5RPDGFRB | |
| SCHEMBL4673278 | 0.84 | KMT2A (0.49) | KMT2AGAAMAPTCA12CA1 | |
| SCHEMBL4675351 | 0.84 | KMT2A (0.49) | KMT2AGAAMAPTCA12CA1 | |
| SCHEMBL8096541 | 0.79 | FAAH (0.51) | KMT2AFAAHGAANPY5RPDGFRB | |
| SCHEMBL7314720 | 0.78 | ALDH1A1 (0.48) | MAPTRECQLSMN1; SMN2MMP1MMP2 | |
| SCHEMBL7314715 | 0.78 | ALDH1A1 (0.48) | MAPTRECQLSMN1; SMN2MMP1MMP2 | |
| SCHEMBL8096543 | 0.76 | FAAH (0.49) | KMT2AFAAHGAANPY5RPDGFRB | |
| SCHEMBL4673443 | 0.74 | MMP1 (0.53) | KMT2AGAAMAPTCA12CA1 | |
| SCHEMBL4673444 | 0.74 | MMP1 (0.53) | KMT2AGAAMAPTCA12CA1 | |
| SCHEMBL311835 | 0.73 | SMN1; SMN2 (0.66) | KMT2AFAAHPDGFRBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |