Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319451 | 0.79 | KMT2A (0.50) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL4672695 | 0.79 | KMT2A (0.50) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL8104005 | 0.78 | ALDH1A1 (0.46) | GAA | |
| SCHEMBL8096543 | 0.77 | FAAH (0.49) | FAAHCA12CA1CA2CA9 | |
| SCHEMBL311835 | 0.72 | SMN1; SMN2 (0.66) | FAAHKMT2APDGFRB | |
| SCHEMBL9467061 | 0.72 | MAPT (0.74) | FAAHKMT2APDGFRB | |
| SCHEMBL4676015 | 0.69 | FAAH (0.61) | FAAHPDGFRB | |
| SCHEMBL20236423 | 0.69 | FAAH (0.61) | FAAHPDGFRB | |
| SCHEMBL4676020 | 0.69 | POLB (0.73) | FAAHPDGFRB | |
| SCHEMBL22218259 | 0.68 | FAAH (0.60) | FAAHNPY5RPDGFRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |