Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095438 | 0.85 | LMNA (0.52) | LMNAPBRM1RIPK1HRH1HTR2A | |
| SCHEMBL8101789 | 0.83 | LMNA (0.52) | LMNAPBRM1HRH1HTR2AMIF | |
| SCHEMBL8086502 | 0.80 | ALDH1A1 (0.49) | LMNAPBRM1HRH1HTR2ASIGMAR1 | |
| SCHEMBL8096631 | 0.78 | LMNA (0.45) | LMNAHTR2ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL10238609 | 0.75 | LMNA (0.50) | LMNAPBRM1RIPK1HKDC1TRPA1 | |
| Phosphonic Acid SCHEMBL9264939 | 0.73 | ALDH1A1 (0.47) | LMNAKDM4EALDH1A1POLB | |
| Diethylamine SCHEMBL11106466 | 0.73 | ALDH1A1 (0.50) | LMNAHRH1HTR2AKDM4EALDH1A1 | |
| SCHEMBL7766694 | 0.71 | HRH1 (0.56) | LMNAHRH1HTR2ASIGMAR1ALDH1A1 | |
| SCHEMBL3646327 | 0.69 | TAAR1 (0.48) | LMNAPBRM1HRH1HTR2AAOC3 | |
| SCHEMBL3861713 | 0.69 | HKDC1 (0.55) | LMNAHRH1HTR2AMIFHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509357-B1 | Polyisobutylene based block copolymers | BAYER RUBBER INC (CA) | 1996-06-05 | — | — | EP | disclosed |
| US-5362817-A | Polyisobutylene based block copolymers | POLYSAR RUBBER CORPORATION (CA) | 1994-11-08 | — | — | US | disclosed |
| US-5260383-A | Reacting polyisobutylene having terminal allyl halogen groups with a living alkali metal-terminated polymer to form star block copolymer | POLYSAR RUBBER CORPORATION (CA) | 1993-11-09 | — | — | US | disclosed |
| EP-0509357-A1 | Polyisobutylene based block copolymers | BAYER RUBBER INC. (CA) | 1992-10-21 | — | — | EP | disclosed |