⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707463 | 0.85 | NPSR1 (0.33) | — | |
| SCHEMBL10710358 | 0.85 | — | — | |
| SCHEMBL10707986 | 0.71 | NPSR1 (0.31) | — | |
| SCHEMBL18074304 | 0.70 | PABPC1 (0.33) | — | |
| SCHEMBL12014244 | 0.68 | CRBN (0.33) | — | |
| SCHEMBL10709544 | 0.68 | — | — | |
| SCHEMBL20956911 | 0.67 | P2RX7 (0.33) | — | |
| SCHEMBL10706340 | 0.65 | — | — | |
| SCHEMBL10707469 | 0.65 | LMNA (0.37) | — | |
| SCHEMBL28251386 | 0.63 | MAPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087499-A | REACTION OF PERFLUOROALKYLACRYLIC ACID WITH UREA AND ACETIC ANHYDRIDE | F-TECH INCORPORATED (JP) | 2000-07-11 | — | — | US | disclosed |
| EP-0103436-B1 | PROCESS FOR PREPARING 5-PERFLUOROALKYL-5,6-DIHYDROURACIL DERIVATIVES AND COMPOUNDS FOR USE THEREIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4581452-A | ANTICARCINOGENIC, ANTITUMOR AGENTS; CYCLIZATION | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0103436-A2 | Process for preparing 5-perfluoroalkyl-5,6-dihydrouracil derivatives and compounds for use therein | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1984-03-21 | — | — | EP | disclosed |