Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603037 | 0.83 | SMN1; SMN2 (0.39) | EPHX1CHRNB2CHRNA4 | |
| SCHEMBL8628389 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL10553590 | 0.78 | ACHE (0.47) | EPHX1 | |
| SCHEMBL19741597 | 0.77 | EPHX1 (0.32) | EPHX1CHRNB2CHRNA4 | |
| SCHEMBL20496737 | 0.76 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL18918481 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL7179413 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL5324380 | 0.70 | CTSK (0.46) | EPHX1CYP1A2CHRNB2CHRNA4 | |
| SCHEMBL5639012 | 0.69 | — | — | |
| SCHEMBL28070032 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700951-B1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KK (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0700951-A1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5491203-A | COMPRISES POLYSILSESQUIOXANE STRUCTURE; HAS METHYL GROUP AND A REACTIVE GROUP ON SIDE CHAINS; SUITABLE AS POLYMER MODIFIER; CROSSLINKING; COATINGS | SHOWA DENKO K. K. (JP) | 1996-02-13 | — | — | US | disclosed |