SCHEMBL19741597

SCHEMBL19741597

CCC(OC(=O)NC)[Si](OC)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.32
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20496737 0.83 EPHX1 (0.32) EPHX1
SCHEMBL82327 0.78 TSHR (0.37)
SCHEMBL8096900 0.77 EPHX1 (0.32) EPHX1CHRNB2CHRNA4
SCHEMBL8839156 0.76 MEN1 (0.33)
SCHEMBL2702039 0.76 LMNA (0.35)
SCHEMBL11028041 0.76 TSHR (0.37)
SCHEMBL4412389 0.76 TSHR (0.36)
SCHEMBL1071091 0.76 MGAM (0.45)
SCHEMBL28379558 0.74
SCHEMBL4312022 0.74 HCAR2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336856-B2 Alkoxysilane- and allophanate-functionalized coating materials EVONIK DEGUSSA GMBH (DE) 2019-07-02 US disclosed
US-10336854-B2 Alkoxysilane-functionalized and allophanate-functionalized urethanes EVONIK DEGUSSA GMBH (DE) 2019-07-02 US disclosed
US-10093826-B2 Alkoxysilane-functionalized allophanate-containing coating compositions EVONIK DEGUSSA GMBH (DE) 2018-10-09 US disclosed
US-10093765-B2 Alkoxysilane-functionalized allophanates EVONIK DEGUSSA GMBH (DE) 2018-10-09 US disclosed
US-20170369736-A1 ALKOXYSILANE-FUNCTIONALIZED ALLOPHANATE-CONTAINING COATING COMPOSITIONS EVONIK DEGUSSA GMBH (DE) 2017-12-28 US disclosed
US-20170369631-A1 ALKOXYSILANE- AND ALLOPHANATE-FUNCTIONALIZED COATING MATERIALS EVONIK DEGUSSA GMBH (DE) 2017-12-28 US disclosed
US-20170369627-A1 ALKOXYSILANE-FUNCTIONALIZED AND ALLOPHANATE-FUNCTIONALIZED URETHANES EVONIK DEGUSSA GMBH (DE) 2017-12-28 US disclosed
US-20170369626-A1 ALKOXYSILANE-FUNCTIONALIZED ALLOPHANATES EVONIK DEGUSSA GMBH (DE) 2017-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336856-B2 Alkoxysilane- and allophanate-functionalized coating materials DDAH1, OR10J3, AP3S1 EPHX1 2768/4885CHRNB2 1125/4885CHRNA4 1955/4885
US-20170369626-A1 ALKOXYSILANE-FUNCTIONALIZED ALLOPHANATES OR10J3, NOS3, NOX3 EPHX1 1939/4885CHRNB2 1114/4885CHRNA4 1502/4885
US-10093826-B2 Alkoxysilane-functionalized allophanate-containing coating compositions DDAH1, OR10J3, AP3S1 EPHX1 3064/4885CHRNB2 637/4885CHRNA4 1210/4885
US-10093765-B2 Alkoxysilane-functionalized allophanates OR10J3, NOS3, NOX3 EPHX1 1939/4885CHRNB2 1114/4885CHRNA4 1502/4885
US-10336854-B2 Alkoxysilane-functionalized and allophanate-functionalized urethanes ALKBH3, PUF60, SDC2 EPHX1 1685/4885CHRNB2 1703/4885CHRNA4 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.