Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105439 | 0.91 | GAA (0.47) | LMNATSHRGAAATMALDH1A1 | |
| SCHEMBL8099200 | 0.88 | GAA (0.47) | GAASMYD3POLBALDH1A1KMT2A | |
| SCHEMBL8098702 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL8098460 | 0.87 | NTMT1 (0.35) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8102959 | 0.87 | SMN1; SMN2 (0.38) | LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8099147 | 0.86 | POLB (0.41) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL8097382 | 0.86 | FAAH (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8096915 | 0.86 | ALDH1A1 (0.38) | LMNAALOX5ATMALDH1A1KMT2A | |
| SCHEMBL8105978 | 0.86 | TP53 (0.42) | LMNAPOLBTDP1ALDH1A1MAPT | |
| SCHEMBL8099477 | 0.85 | SMN1; SMN2 (0.40) | LMNATSHRALOX5GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |