Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098702 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8098460 | 0.89 | NTMT1 (0.35) | MAPTALDH1A1KDM4E | |
| SCHEMBL8096915 | 0.88 | ALDH1A1 (0.38) | ALDH1A1LMNAL3MBTL1HSD11B1 | |
| SCHEMBL8099147 | 0.88 | POLB (0.41) | MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8097382 | 0.88 | FAAH (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL8105978 | 0.88 | TP53 (0.42) | MAPTALDH1A1LMNA | |
| SCHEMBL8097540 | 0.87 | POLB (0.36) | SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL8097004 | 0.87 | LMNA (0.44) | SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8097595 | 0.86 | KMT2A (0.37) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL8105439 | 0.86 | GAA (0.47) | SMN1; SMN2MAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |