Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084731 | 0.90 | CACNA1C (0.46) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL8091377 | 0.88 | SMN1; SMN2 (0.51) | KDM4EHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL8100065 | 0.88 | TP53 (0.51) | KDM4EHSD17B10TP53MAPTCASP1 | |
| SCHEMBL8099097 | 0.87 | SMN1; SMN2 (0.52) | KDM4EHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL8913648 | 0.84 | ADORA3 (0.52) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL13285115 | 0.81 | CYP2C9 (0.67) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL7884089 | 0.81 | NR1I2 (0.59) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL6945817 | 0.79 | ALOX15 (0.51) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL27439079 | 0.79 | CACNA1C (0.45) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 | |
| SCHEMBL11683102 | 0.77 | KDM4E (0.59) | KDM4EHSD17B10CYP2C9CYP1A2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066655-A | FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, IN PARTICULAR AS CEREBRAL THERAPEUTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5731333-A | LEARNING AND MEMORY ENHANCEMENT, ANTIDEPRESSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |