Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105795 | 0.85 | ACHE (0.35) | ALDH1A1 | |
| SCHEMBL8097763 | 0.85 | CYP1A2 (0.38) | MEN1KMT2AMAPTCYP1A2TDP1 | |
| SCHEMBL10387393 | 0.72 | MEN1 (0.43) | TAAR1MEN1KMT2AGAAMAPT | |
| SCHEMBL8155665 | 0.72 | TAAR1 (0.41) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL27214925 | 0.68 | KMT2A (0.43) | TAAR1MEN1KMT2AGAAMAPT | |
| SCHEMBL27231035 | 0.68 | KMT2A (0.43) | TAAR1MEN1KMT2AGAAMAPT | |
| SCHEMBL3842933 | 0.68 | TAAR1 (0.38) | TAAR1MEN1KMT2AGAAMAPT | |
| SCHEMBL158972 | 0.68 | GABRA1 (0.46) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL29812934 | 0.68 | GABRA1 (0.46) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL29648809 | 0.68 | GABRA1 (0.47) | TAAR1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |