Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097830 | 0.85 | TAAR1 (0.37) | ALDH1A1 | |
| SCHEMBL8107147 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL1547829 | 0.70 | ACHE (0.39) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL8097763 | 0.70 | CYP1A2 (0.38) | ALDH1A1 | |
| SCHEMBL38659149 | 0.69 | ALDH1A1 (0.43) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL4081893 | 0.69 | CES2 (0.39) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL835486 | 0.65 | CES2 (0.42) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL363206 | 0.65 | CES2 (0.36) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL10820270 | 0.65 | CES2 (0.36) | ACHECES2CES1ALDH1A1 | |
| SCHEMBL12329402 | 0.62 | ACHE (0.48) | ACHECES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | claimed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | claimed |
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |