Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201000 | 0.83 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL8373375 | 0.82 | GSK3B (0.43) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL8094674 | 0.79 | CUL4A (0.43) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL29137860 | 0.77 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL2483769 | 0.74 | CUL4A (0.47) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL8745445 | 0.74 | MEN1 (0.36) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL8373379 | 0.68 | POLB (0.46) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL8651250 | 0.67 | GSK3B (0.61) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL5010509 | 0.65 | GSK3B (0.59) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL27574798 | 0.64 | LMNA (0.35) | MAPTKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755185-B1 | Use of Dibromo-thiophen-carboxylic acid derivatives as microbicides | BAYER AG (DE) | 2000-12-13 | — | — | EP | disclosed |
| EP-0755185-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027397-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |
| EP-0450355-B1 | Compounds for the combat against plant diseases | DEGUSSA (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0450355-A1 | Compounds for the combat against plant diseases | Degussa Aktiengesellschaft (DE) | 1991-10-09 | — | — | EP | disclosed |