Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098035 | 0.83 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL8373375 | 0.82 | GSK3B (0.43) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL9158487 | 0.80 | DAO (0.34) | GSK3B | |
| SCHEMBL8094674 | 0.79 | CUL4A (0.43) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL29137860 | 0.77 | GSK3B (0.41) | GSK3BMEN1KMT2AMAPTPOLB | |
| SCHEMBL6959745 | 0.76 | — | — | |
| SCHEMBL6958300 | 0.76 | KEAP1 (0.35) | PKM | |
| SCHEMBL6970016 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL6964660 | 0.74 | — | — | |
| SCHEMBL2483769 | 0.74 | CUL4A (0.47) | GSK3BMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863766-B1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | GILEAD CONNECTICUT INC (US) | 2015-05-20 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-0755185-B1 | Use of Dibromo-thiophen-carboxylic acid derivatives as microbicides | BAYER AG (DE) | 2000-12-13 | — | — | EP | disclosed |
| EP-0379003-B1 | Thiophene-2-carboxylic-acid derivatives, process for their preparation and their use in combating undesired plant growth | BASF AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| EP-0379003-A1 | Thiophene-2-carboxylic-acid derivatives, process for their preparation and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |