Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098042 | 0.94 | NOS3 (0.33) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL8090090 | 0.85 | NPY4R (0.32) | ALDH1A1RAB9ASPHK1 | |
| SCHEMBL8091555 | 0.85 | CTSB (0.33) | ALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8091676 | 0.83 | L3MBTL1 (0.32) | ALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8083593 | 0.82 | L3MBTL1 (0.32) | ALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8095460 | 0.80 | ALDH1A1 (0.31) | ALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8090092 | 0.79 | NPY4R (0.31) | ALDH1A1 | |
| SCHEMBL8091597 | 0.79 | SPHK1 (0.34) | SPHK2SPHK1 | |
| SCHEMBL8091556 | 0.78 | CTSB (0.33) | ALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8091585 | 0.77 | SPHK1 (0.31) | RAB9ASPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |