Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675739 | 0.76 | SMN1; SMN2 (0.44) | KMT2APOLBL3MBTL1KDM4EMEN1 | |
| SCHEMBL6676941 | 0.76 | TRPA1 (0.47) | KMT2APOLBL3MBTL1KDM4EMEN1 | |
| SCHEMBL4397164 | 0.75 | HDAC1 (0.58) | HTTKMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL6674068 | 0.75 | POLB (0.46) | HTTKMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL6674764 | 0.72 | POLB (0.45) | HTTKMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL11706325 | 0.70 | CA12 (0.45) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3567620 | 0.68 | MEN1 (0.53) | HTTKMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL7222675 | 0.67 | TSHR (0.53) | KMT2APOLBL3MBTL1KDM4EMEN1 | |
| SCHEMBL16675446 | 0.65 | HTT (0.69) | HTTKMT2APOLBL3MBTL1KDM4E | |
| SCHEMBL7158029 | 0.65 | RARA (0.67) | KMT2APOLBL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051713-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION, PARTICULARLY AS AGENTS FOR TREATING SKIN RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, INFLAMMATORY AND NON-KERATINIZATION SKIN DISORDERS | ALLERGAN SALES, INC. (US) | 2000-04-18 | — | — | US | disclosed |