Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098343 | 1.00 | HRH3 (0.33) | HRH3FNTAFNTBS1PR1CYP11B1 | |
| SCHEMBL8097062 | 0.91 | CYP19A1 (0.36) | FNTAFNTBCYP19A1 | |
| SCHEMBL8097065 | 0.91 | CYP19A1 (0.36) | FNTAFNTBCYP19A1 | |
| SCHEMBL8103769 | 0.91 | CYP19A1 (0.36) | FNTAFNTBCYP19A1 | |
| SCHEMBL8098378 | 0.90 | CYP11B1 (0.34) | HRH3FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL8098386 | 0.90 | CYP11B1 (0.34) | HRH3FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL8095949 | 0.89 | FNTA (0.37) | FNTAFNTBS1PR1CYP11B1CYP11B2 | |
| SCHEMBL8095942 | 0.89 | FNTA (0.37) | FNTAFNTBS1PR1CYP11B1CYP11B2 | |
| SCHEMBL8097906 | 0.87 | L3MBTL1 (0.39) | HRH3FNTAFNTBCHRM4CYP19A1 | |
| SCHEMBL8097913 | 0.87 | L3MBTL1 (0.39) | HRH3FNTAFNTBCHRM4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |