Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098482 | 0.87 | MAPT (0.39) | RHOCRHOANPC1KMT2AMEN1 | |
| SCHEMBL8098738 | 0.83 | CYP1A2 (0.33) | KCNH2 | |
| SCHEMBL8083938 | 0.82 | RHOC (0.35) | RHOCRHOAL3MBTL1DRD2NPC1 | |
| SCHEMBL8083652 | 0.81 | PPARG (0.36) | PPARGPPARDKMT2AMEN1MAPT | |
| SCHEMBL8098272 | 0.81 | UBE2M (0.34) | NPSR1L3MBTL1PPARGPPARAPPARD | |
| SCHEMBL8098790 | 0.78 | NPSR1 (0.36) | NPSR1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL8090776 | 0.78 | PTGER4 (0.38) | PPARGKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8083716 | 0.77 | AKR1C3 (0.37) | PPARGNPC1KMT2AMEN1KDM4E | |
| SCHEMBL7920418 | 0.76 | HDAC1 (0.38) | NPC1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8342163 | 0.72 | SERPINE1 (0.37) | NPSR1NPC1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |