Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513146 | 0.92 | RAPGEF4 (0.68) | RAPGEF4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL15145097 | 0.82 | ALDH1A1 (0.58) | RAPGEF4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30542248 | 0.81 | HPGD (0.60) | MAPK13MAPK12MAPK11MAPK14HPGD | |
| SCHEMBL331059 | 0.81 | ALDH1A1 (0.59) | RAPGEF4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4826082 | 0.81 | HPGD (0.60) | MAPK13MAPK12MAPK11MAPK14HPGD | |
| SCHEMBL26510737 | 0.78 | RAPGEF4 (0.73) | RAPGEF4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9218756 | 0.78 | RAPGEF4 (0.53) | RAPGEF4MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL14062099 | 0.78 | HPGD (0.56) | MAPK13MAPK12MAPK11MAPK14HPGD | |
| SCHEMBL29267932 | 0.78 | ALDH1A1 (0.69) | MAPK13MAPK12MAPK11MAPK14HPGD | |
| Methyl Alcohol SCHEMBL9305637 | 0.77 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613504-A1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | Johnson Matthey Public Limited Company (GB) | 2020-02-26 | — | — | EP | disclosed |
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| US-20190016742-A1 | Complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-17 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167305-B2 | Allyl complexes for use in coupling reactions | AP3M1, AP1M1, C9 | RAPGEF4 2684/4885MAPK13 3471/4885MAPK12 3633/4885 |
| US-20190016742-A1 | Complexes | C5, C1S, C9 | RAPGEF4 2359/4885MAPK13 4403/4885MAPK12 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.