SCHEMBL9218756

SCHEMBL9218756

Cc1ccc(Nc2ccc(N=O)cc2)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.53
ALDH1A1 P00352 4/20 0.52
HTT P42858 3/20 0.52
HSD17B10 Q99714 2/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
DHODH Q02127 1/20 0.43
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513146 0.85 RAPGEF4 (0.68) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL9222866 0.84 ALDH1A1 (0.57) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL29467776 0.81 ALDH1A1 (0.53) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL28726135 0.79 ALDH1A1 (0.52) ALDH1A1HTTHSD17B10CYP3A4TSHR
SCHEMBL14256816 0.79 HTR3E (0.50) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL26186667 0.79 MEN1 (0.49) RAPGEF4ALDH1A1HTTHSD17B10TSHR
SCHEMBL8098491 0.78 RAPGEF4 (0.59) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL15145097 0.77 ALDH1A1 (0.58) RAPGEF4ALDH1A1HTTCYP3A4TDP1
SCHEMBL16601890 0.76 ALDH1A1 (0.52) RAPGEF4ALDH1A1HTTHSD17B10CYP3A4
SCHEMBL11548264 0.75 ALDH1A1 (0.65) ALDH1A1HTTHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 EP claimed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP claimed
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 EP disclosed
US-5318882-A Nitrosodiphenylamine compounds render dyes lightfast TAIYO YUDEN CO., LTD. (JP) 1994-06-07 US disclosed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP disclosed